Determination of benzophenones in a cosmetic matrix by supercritical fluid extraction and capillary electrophoresis
| Autor: | Shu-Ping Wang, Wen-Tsong Lee |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Chromatography
Resolution (mass spectrometry) Chemistry Organic Chemistry Supercritical fluid extraction Electrophoresis Capillary Chromatography Supercritical Fluid General Medicine Biochemistry High-performance liquid chromatography Supercritical fluid Analytical Chemistry Matrix (chemical analysis) Benzophenones chemistry.chemical_compound Capillary electrophoresis Sample preparation Polysorbate 20 Sunscreening Agents |
| Zdroj: | Journal of Chromatography A. 987:269-275 |
| ISSN: | 0021-9673 |
| DOI: | 10.1016/s0021-9673(02)01821-6 |
| Popis: | Benzophenones are common additives in commercial sunscreen products. These UV absorbers were extracted by supercritical fluid extraction (SFE), and then analyzed by capillary zone electrophoresis (CZE) and high-performance liquid chromatography. This study was applied to identify the contents of benzophenones in cosmetic matrix, and simultaneously, to investigate the behavior of migration in CZE. Adding non-ionic surfactant (Tween 20) to optimize the separation in the CZE operation improves resolution. In SFE, we chose carbon dioxide with 2.5% modifier of 10% aqueous phosphoric acid-MeOH (1:1) as the supercritical fluid. Real recoveries of up to 92% with relative standard deviations of less than 4.0% were achieved. These analytical techniques were also applied to assay benzophenones for ten commercial sunscreen cosmetics. We found benzophenone 3 was the most commonly used sunscreen additive in Taiwan. |
| Databáze: | OpenAIRE |
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