Neuropsychiatric Symptoms Among Hispanics: Results of the Maracaibo Aging Study
| Autor: | Ledys Mata, Mario Gil, Gabriel A. de Erausquin, Vincent P. Diego, Rosa V. Pirela, Ciro Gaona, Jesus D. Melgarejo, Gladys E. Maestre, Carlos A. Chavez, Juan Carlos López-Alvarenga, Ney Alliey-Rodriguez |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Aging Clinical Dementia Rating Irritability Euphoriant Article 03 medical and health sciences 0302 clinical medicine mental disorders medicine Humans Dementia Cognitive Dysfunction Apathy Longitudinal Studies Prospective Studies 030212 general & internal medicine Stroke Depression (differential diagnoses) Aged Psychiatric Status Rating Scales business.industry Mental Disorders General Neuroscience Hispanic or Latino General Medicine Middle Aged Venezuela medicine.disease Psychiatry and Mental health Clinical Psychology Cross-Sectional Studies Anxiety Female Geriatrics and Gerontology medicine.symptom business 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | J Alzheimers Dis |
| ISSN: | 1875-8908 1387-2877 |
| DOI: | 10.3233/jad-201144 |
| Popis: | Background: Neuropsychiatric symptoms play an important role in diagnosing and clinical follow-up of cognitive impairment and dementia. Objective: We investigated the relationship between neuropsychiatric symptoms, cognitive impairment, and dementia in Hispanics. Methods: We included 529 participants (age ≥40 years) from the Maracaibo Aging Study with standardized neuropsychiatric assessments, including the Neuropsychiatric Inventory (NPI). Based on the Clinical Dementia Rating and the Mini-Mental State Examination scores, participants’ cognitive status was categorized into normal cognition, mild/moderate, and severe cognitive impairment. Diagnosis of dementia was established in a consensus conference. Statistical analyses included multivariable logistic regression models and area under the curve (AUC). Results: The mean age of participants was 59.3 years, and 71.8%were women. The proportion of dementia was 6.8%. Disturbed sleep, anxiety, and depression were the most common neuropsychiatric symptoms in the study sample. In crude analyses, the proportions of hallucinations, aberrant motor behavior, agitation/aggression, apathy, delusions, irritability, eating disturbance, depression, and euphoria were differently distributed among cognitive status groups (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|