The Nose as a Route for Therapy: Part 1. Pharmacotherapy
Autor: | Nuray Bayar Muluk, Nikolaos G. Papadopoulos, Anu Laulajainen-Hongisto, Ludger Klimek, Maija Hytönen, Glenis K. Scadding, Dimitrios Mitsias, Cemal Cingi, Sanna Toppila-Salmi |
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Přispěvatelé: | HUS Head and Neck Center, Korva-, nenä- ja kurkkutautien klinikka, Clinicum, HUS Inflammation Center, Department of Pathology, Department of Dermatology, Allergology and Venereology, Medicum |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
business.industry
Mucociliary clearance Nasal structure Nasal epithelium 3. Good health 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Pharmacotherapy 030228 respiratory system Anesthesia medicine otorhinolaryngologic diseases Nasal administration 3125 Otorhinolaryngology ophthalmology 030223 otorhinolaryngology Adverse effect business Sinus (anatomy) Nose |
Popis: | This article reviews nasal structure and function in the light of intranasal pharmacotherapy. The nose provides an accessible, fast route for local treatment of nose and sinus diseases, with lower doses than are necessary systemically and few adverse effects. It can also be used for other medications as it has sufficient surface area protected from local damage by mucociliary clearance, absence of digestive enzymes, responsive blood flow, and provides a rapid route to the central nervous system. |
Databáze: | OpenAIRE |
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