Thymic carcinoid and parathyroid hyperplasia detection with 99mTc-MIBI men type 1
| Autor: | J.C Martín, A. Flotats, Ll Bernà, J. León, Carina Mari, A. Tembl, X. Matis-Guiu, J. Farrerons |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Diarrhea Male Pathology medicine.medical_specialty Endocrinology Diabetes and Metabolism Radiography Carcinoid Tumor Scintigraphy Mediastinal Neoplasms Parathyroid Glands Lesion Kidney Calculi Endocrinology Multiple Endocrine Neoplasia Type 1 Humans Medicine Radionuclide Imaging Hyperparathyroidism Hyperplasia medicine.diagnostic_test business.industry Thymus Neoplasms medicine.disease medicine.anatomical_structure Endocrine pathology Parathyroid gland medicine.symptom business Primary hyperparathyroidism |
| Zdroj: | Journal of Endocrinological Investigation. 22:803-807 |
| ISSN: | 1720-8386 0391-4097 |
| Popis: | We report a case of a 35-year-old male, with a history of diarrhea, renal lithiasis with frequent expulsions of calculus and hypercalcemia during the last 2 years. The patient was studied and diagnosed with a multiple endocrine neoplasia type I (MEN I), familiar (mother with MEN I). A scintigraphic study with 99mTc-MIBI was performed in order to localize hyperfunctioning parathyroid glands because of biochemical diagnosis of primary hyperparathyroidism. Double phase 99mTc-MIBI scan detected one hyperfunctioning parathyroid gland and a large anterior mediastinal mass. Subsequent, plain radiograph and CT of the chest showed a soft-tissue mass in that localization. Punch biopsy of the lesion guided by CT revealed malignant cells of neuroendocrine tumor. The tumor was removed and histologically confirmed as a carcinoid within a thymus in a MEN type I syndrome. MEN I patients can benefit from the examination with this agent which can potentially localize not only parathyroid endocrine pathology but also unknown associated tumors. |
| Databáze: | OpenAIRE |
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