Changes in muscle compartment pressure after cardiopulmonary bypass
| Autor: | Bjarni Torfason, Líney Símonardóttir, Einar Stefánsson, Jónas Magnússon |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
Intraocular pressure medicine.medical_specialty Serum albumin Hemodynamics 030204 cardiovascular system & hematology law.invention 03 medical and health sciences 0302 clinical medicine law Edema Pressure Cardiopulmonary bypass Humans Medicine Mannitol Radiology Nuclear Medicine and imaging Muscle Skeletal Intraocular Pressure Serum Albumin Aged Inflammation Advanced and Specialized Nursing Hemodilution Cardiopulmonary Bypass biology business.industry General Medicine Middle Aged Diuretics Osmotic Cardiac surgery 030228 respiratory system Anesthesia biology.protein Arterial line Female Leukocyte Reduction Procedures medicine.symptom Cardiology and Cardiovascular Medicine business Safety Research Perfusion |
| Zdroj: | Perfusion. 21:157-163 |
| ISSN: | 1477-111X 0267-6591 |
| DOI: | 10.1191/0267659106pf861oa |
| Popis: | Purpose: Hemodilution and inflammation lead to edema and increased muscle compartment pressure after cardiac surgery. The aim of this study was to find whether muscle compartment pressure was affected by the addition of albumin and mannitol to the pump prime, heparin coating or leukocyte depletion. Additionally, we studied the relationship between intraocular pressure and lower leg muscle compartment pressure. Edema during and following cardiac surgery is due to hemodynamic, osmotic and inflammatory changes, according to Starling’s Law. We attempted to influence the osmotic balance and reduce the inflammatory response in order to reduce the edema. Methods: Thirty-six patients who underwent cardiac surgery were randomly allocated into four groups. Group A received albumin and mannitol into the pump prime. Group B had an, heparin-coated perfusion system, Group C had a leukocyte-depletion arterial line filter and Group D was the control group, where intraocular pressure was also measured. Results: Lower leg muscle compartment pressure increased significantly during and after cardiac surgery in all groups, but this increase was significantly less in Group A than in the control group 24 h after surgery. No correlation was found between muscular compartment pressure and intraocular pressure. The intraocular pressure profile is different from the muscular compartment pressure and recovers much faster. Conclusion: Lower leg muscle compartment pressure and intraocular pressure behave differently during and after cardiac surgery. Albumin and mannitol added to the pump prime decreases muscle compartment pressure after cardiac surgery. |
| Databáze: | OpenAIRE |
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