Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
| Autor: | Gabriela Hemylin Ferreira Moura, João Marcelo Azevedo de Paula Antunes, Heider Irinaldo Pereira Ferreira, Jacqueline Kazue Kurissio, Ilanna Vanessa Pristo de Medeiros Oliveira, Célio Souza da Rocha, Débora Alves de Carvalho Freire, Cecilia Calabuig, João Pessoa Araújo Júnior |
|---|---|
| Přispěvatelé: | Universidade Federal Rural do Semi-Árido – UFERSA, Universidade Estadual Paulista (Unesp) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Feline immunodeficiency virus 040301 veterinary sciences viruses Feline panleukopenia Abortion Article Virus 0403 veterinary science 03 medical and health sciences Monocytosis medicine Felis catus reproductive and urinary physiology Reproductive failures CATS lcsh:Veterinary medicine General Veterinary biology business.industry Gestational age 04 agricultural and veterinary sciences biology.organism_classification medicine.disease Virology Neutrophilia 030104 developmental biology Infectious causes Loss of pregnancy lcsh:SF600-1100 Animal Science and Zoology medicine.symptom business |
| Zdroj: | Veterinary and Animal Science, Vol 6, Iss, Pp 75-80 (2018) Veterinary and Animal Science Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Highlights • CPPV-1 was found in all females of the study, tested with qPCR. • Was found CPPV-1 in fetal/maternal tissue in the post-mortem examination. • Feline females (with and without Reproductive Failures) were negative for commonly-occurring RF viruses in the same (FIV, FeLV e FHV-1). • Females showed clinical signs only related to RF and abnormalities WBCC. • These results provide the first description of an FPV agent causing only RF-related clinical signs in queens. Although reproductive failures (RF) such as abortion, stillbirth and neonatal mortality in cats are still under researched, it is known that many RF are caused by viral agents. This research surveyed the viral agent prevalence in queens with RF. Queens were excluded from the study if their RF was caused by issues other than infection, such as genetic, traumatic, hormonal or nutritional problems, or if they had a history of RF. Blood samples from 26 pregnant females with RF were collected for complete blood counts (BCC), renal/hepatic biochemistry and glycaemic analysis. Ultrasonography was performed to evaluate gestational age and foetal viability. When possible, placentas, humours and foetal tissues were collected. Blood samples were tested by PCR and qPCR for feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV), feline alphaherpesvirus 1 (FeHV-1) and carnivore protoparvovirus 1 (CPPV-1). All maternal samples were negative for FeLV, FIV and FeHV-1 and positive for CPPV-1. In addition, foetuses from one queen and three females were positive for CPPV-1 by qPCR and for feline panleukopenia virus (FPV) through DNA sequencing. The BCC and biochemistry results revealed significant neutrophilia, lymphopenia, monocytosis, and liver enzymes. These results provide the first description of an FPV agent causing only RF-related clinical signs in queens. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|