Secondary Skin Cancer in a Case with Long-term Voriconazole after Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia

Autor:	Noriaki, Kawano, Shunou, Nakamura, Kousuke, Mochida, Shuro, Yoshida, Takuro, Kuriyama, Takashi, Nakaike, Tomonori, Shimokawa, Taro, Tochigi, Kiyoshi, Yamashita, Koichi, Mashiba, Ikuo, Kikuchi, Aina, Takarabe, Sayaka, Moriguchi, Yasuo, Mori, Katsuto, Takenaka, Kazuya, Shimoda, Hidenobu, Ochiai, Masahiro, Amano
Rok vydání:	2022
Předmět:	Male Leukemia Myeloid Acute Skin Neoplasms Hematopoietic Stem Cell Transplantation Internal Medicine Graft vs Host Disease Humans Transplantation Homologous Voriconazole General Medicine Middle Aged Retrospective Studies
Zdroj:	Internal Medicine. 61:2771-2774
ISSN:	1349-7235 0918-2918
DOI:	10.2169/internalmedicine.8618-21
Popis:	Secondary malignancies that develop after allogeneic-hematopoietic stem cell transplantation (allo-HSCT) have become serious issues. A 47-year-old man who developed acute myeloid leukemia in 2009 and subsequently underwent allo-HSCT twice: in 2009 and 2011. In 2015, voriconazole for lung aspergillus was started. In 2018, chronic graft-versus-host disease (GVHD) and multiple actinic keratoses manifested at his head. In 2020, some lesions were diagnosed as squamous cell carcinoma, so voriconazole was withdrawn, and subsequent surgery and radiation led to remission. Long-term administration of voriconazole in addition to allo-HSCT and chronic GVHD may be closely related to secondary skin cancer.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1419d897684b6c1945539c2048fae5d https://doi.org/10.2169/internalmedicine.8618-21 Zobrazit plný text záznamu