| Autor: |
William P.D. Hendricks, David P. Carbone, Jeffrey M. Trent, Muhammed Murtaza, Timothy G. Whitsett, Krista La Perle, Michael J. Koenig, Sara L. Sinicropi-Yao, Joseph M. Amann, Winnie S. Liang, Kevin Drenner, Shukmei Wong, Salvatore Facista, Alexandra Nazareno, Tania Contente-Cuomo, Nieves Perdigones, Victoria Zismann, Karthigayini Sivaprakasam, Gwendolen Lorch |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1078-0432.22474629.v1 |
| Popis: |
HER2 cellular location and function in primary canine lung cancer. (A) Canine papillary adenocarcinoma with intense, complete, circumferential membrane (white arrow) and lateral cytoplasmic membrane (black arrow) anti-HER2 antibody positive staining (brown) in a patient with wild-type HER2. (B) Canine papillary adenocarcinoma with moderate cytoplasmic (black arrow) anti-HER2 antibody positive staining (light brown) in a patient with wild-type HER2. x 40; bar 50 µm. (C) Anti-HER2 immunohistochemistry of a Grade 1 canine papillary adenocarcinoma wild type for HER2. x 20. (D) Segmentation mark-up of the tumor from adjacent normal lung. Tumor is identified by green, whereas red is area within tumor that contains no tissue, and yellow represents areas of non-tumor such as necrosis or tumor stroma. x20. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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