The myocardial renin-angiotensin system: Existence, importance, and clinical implications
| Autor: | W.Carter Grinstead, James B. Young |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
medicine.medical_specialty
business.industry Angiotensin II Myocardium Angiotensin-Converting Enzyme Inhibitors Biological activity Peptide hormone Myocardial Contraction Renin-Angiotensin System Contractility Endocrinology Myocardial hypertrophy Internal medicine Renin–angiotensin system cardiovascular system medicine Animals Humans Coronary vasoconstriction Angiotensin I Cardiology and Cardiovascular Medicine business Ace inhibition |
| Zdroj: | American Heart Journal. 123:1039-1045 |
| ISSN: | 0002-8703 |
| DOI: | 10.1016/0002-8703(92)90715-8 |
| Popis: | Major components of the renin-angiotensin system have been localized to cardiac tissue. Cardiac-derived angiotensin II may benefit myocardial contractility but may promote detrimental myocardial hypertrophy, coronary vasoconstriction, and arrhythmias. The benefits of ACE inhibition probably extend beyond the classic circulating RAS to include the heart directly. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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