Correlation between pain severity and levels of anxiety and depression in osteoarthritis patients: a systematic review and meta-analysis
| Autor: | Joana Carneiro Pinto, Armando Almeida, Teresa Martins, Diana Fonseca-Rodrigues, Diana Amorim, Filipa Pinto-Ribeiro, André Rodrigues |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
MEDLINE Pain Osteoarthritis Anxiety Hospital Anxiety and Depression Scale Correlation 03 medical and health sciences 0302 clinical medicine Rheumatology Internal medicine medicine Humans Pharmacology (medical) 030212 general & internal medicine Depression (differential diagnoses) Pain Measurement 030203 arthritis & rheumatology business.industry Depression Chronic pain medicine.disease 3. Good health Meta-analysis medicine.symptom business |
| Zdroj: | Rheumatology (Oxford, England). 61(1) |
| ISSN: | 1462-0332 |
| Popis: | Objectives Osteoarthritis (OA) is a chronic degenerative musculoskeletal disease that causes articular damage and chronic pain, with a prevalence of up to 50% in individuals >60 years of age. Patients suffering from chronic painful conditions, including OA, also frequently report anxiety or depression. A systematic review and meta-analysis were performed to assess the correlation between pain severity and depressive and anxious symptomatology in OA patients. Methods A systematic search was conducted using four databases (PubMed, Medline, Scopus, and Web of Science) from inception up to 14 January 2020. We included original articles evaluating pain severity and anxiety and/or depression severity in OA-diagnosed patients. Detailed data were extracted from each study, including patients’ characteristics and pain, anxiety, and depression severity. When available, the Pearson correlation coefficient between pain and depression severity and pain and anxiety severity was collected, and a meta-analysis of random effects was applied. Results This systematic review included 121 studies, with a total of 38 085 participants. The mean age was 64.3 years old, and the subjects were predominantly female (63%). The most-used scale to evaluate pain severity was the Western Ontario and the McMaster Universities Osteoarthritis Index, while for anxiety and depression, the Hospital Anxiety and Depression Scale was the most used. The meta-analysis showed a moderate positive correlation between pain severity and both anxious (r = 0.31, P Conclusion Our results demonstrate a significant correlation between pain and depression/anxiety severity in OA patients, highlighting the need for its routine evaluation by clinicians. |
| Databáze: | OpenAIRE |
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