Treatment of recalcitrant mycosis fungoides with topical gentian violet
| Autor: | Natasha Cowan, Garrett Coman, Keith L. Duffy, David A. Wada |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Erythema CTCL cutaneous T-cell lymphoma Case Report Dermatology GV gentian violet Cutaneous lymphoma 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Biopsy Medicine cutaneous T-cell lymphoma cutaneous lymphoma UVB ultraviolet B Bexarotene Mycosis fungoides treatment medicine.diagnostic_test mycosis fungoides business.industry Cutaneous T-cell lymphoma Topical gentian violet Ultraviolet b NADPH nicotinamide adenine dinucleotide phosphate medicine.disease 030220 oncology & carcinogenesis MF mycosis fungoides medicine.symptom business medicine.drug |
| Zdroj: | JAAD Case Reports |
| ISSN: | 2352-5126 |
| Popis: | We present a case of recalcitrant, localized patch disease in a patient with stage IB (T2, N0, M0) mycosis fungoides (MF) that clinically responded to treatment with topical gentian violet (GV) after undergoing several other therapies, including narrowband ultraviolet B (UVB) therapy and topical clobetasol, bexarotene, and mechlorethamine. A reduction of erythema of her treated patches was noted within 2 months of once-daily application of topical GV, and there was no disease progression. However, subsequent biopsy of the most prominent patch found the presence of active disease despite reduction of erythema. There was a partial clinical response to topical GV, and this report is among the first to describe the safety and efficacy of GV in MF. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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