The history of multiple adverse childhood experiences in patients with schizophrenia is associated with more severe symptomatology and suicidal behavior with gender-specific characteristics
| Autor: | Gabriela B. Caporusso, Linda G. Cozzarin, Federico M. Daray, Romina Farinola, Germán Alberio, Luciana C. Chiapella, Miguel Vallejos, Cintia R. Prokopez, Pamela Fuentes |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Adolescent Argentina Suicide Attempted Suicidal Ideation Young Adult 03 medical and health sciences Sex Factors 0302 clinical medicine Adverse Childhood Experiences Rating scale Surveys and Questionnaires Recall bias Prevalence Humans Medicine In patient Child Abuse Child Biological Psychiatry Retrospective Studies Positive and Negative Syndrome Scale business.industry Healthy subjects Middle Aged medicine.disease 030227 psychiatry Psychiatry and Mental health Cross-Sectional Studies Suicidal behavior Schizophrenia Female Schizophrenic Psychology business 030217 neurology & neurosurgery Clinical psychology |
| Zdroj: | Psychiatry Research. 293:113411 |
| ISSN: | 0165-1781 |
| Popis: | The current study aims to compare the prevalence of adverse childhood experiences (ACEs) between patients with schizophrenia and non-psychiatric control group, and to analyze the association of having suffered multiple ACEs with clinical symptoms of schizophrenia and suicidal behavior. A multicenter, cross-sectional study was conducted across three facilities in Buenos Aires, Argentina. One-hundred patients with schizophrenia and 50 healthy subjects were assessed with the Adverse Childhood Experiences questionnaire (ACE-Q), the Positive and Negative Syndrome Scale (PANSS), and the Columbia-Suicide Severity Rating Scale (C-SSRS). We observed that the prevalence of at least one ACE in schizophrenic patients was almost double in comparison with the non-psychiatric control group. Multiple ACEs were associated with persistent auditory hallucinations and lower negative symptoms in both sexes. Higher frequency of death ideation and a higher number of suicide attempts were reported among women. The strength of this study is the possibility of comparing the presence of ACEs between schizophrenic patients and non-psychiatric control using the same questionnaire in an under-reported sample of low socio-economic patients assisted in public hospitals. A limitation is that the history of ACEs relied on the retrospective assessment of childhood experiences, and adults could over-report ACEs because of recall bias. |
| Databáze: | OpenAIRE |
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