The graphical design space for the primary drying phase of freeze Drying: Factors affecting the dried product layer resistance
| Autor: | Jayasree M, Srinivasan, Gregory A, Sacha, Steven L, Nail |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | International Journal of Pharmaceutics. 630:122417 |
| ISSN: | 0378-5173 |
| DOI: | 10.1016/j.ijpharm.2022.122417 |
| Popis: | An emerging approach to process development of a lyophilized pharmaceutical product is to construct a graphical design space for primary drying as an aid to process optimization. The purpose of this paper is to further challenge the assumption in earlier work that the maximum values of the resistance of dried product layer, R |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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