Effects of estrogen and luteinizing-releasing hormone on chromatin in CA3 region of male rat hippocampus
| Autor: | Dmitar Drekić, Zoran Zorić, Slavoljub Jović, Milica Nikolić, Dejana Cupic-Miladinovic, Bojana Petrović |
|---|---|
| Jazyk: | srbština |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
endocrine system lcsh:Veterinary medicine General Veterinary male rat Heterochromatin medicine.drug_class hippocampus Hippocampus Biology LHRH 3. Good health Chromatin Endocrinology Estrogen Internal medicine medicine CA3 region estrogen lcsh:SF600-1100 hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Veterinarski Glasnik, Vol 69, Iss 3-4, Pp 163-175 (2015) Veterinarski glasnik (2015) 69(3-4):163-175 |
| ISSN: | 2406-0771 0350-2457 |
| Popis: | The structure of heterochromatin protects genome from undesirable recombinations, while estrogen and luteinizing-releasing hormone (LHRH) cause changes in structure of chromatin. The objective of this study was to prove the connection of neonatally applied estrogen and LHRH, with shown effects on chromatin in hippocampus of adult male rats. Stereological results have shown that total surface of neuron area in estrogen treated animals significantly reduced in regard to the control group as well as groups treated with LHRH. The number of heterochromatin granules in either estrogen or LHRH treated groups significantly increased, while in the last fourth group treated with both estrogen and LHRH the difference is even more expressed, both in regard to the control group and other groups. [Projekat Ministarstva nauke Republike Srbije, br. 173034] |
| Databáze: | OpenAIRE |
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