New pentahydroxylated steroids from the South China Sea gorgonian Subergorgia suberosa
| Autor: | Li-Dan Tang, Shui-Lian Jian, Yuan-Wei Liang, Yonghong Liu, Xiao-Jian Liao, Shi-Hai Xu |
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| Rok vydání: | 2012 |
| Předmět: |
China
South china Magnetic Resonance Spectroscopy Ethanol Molecular Structure Oceans and Seas Bioengineering Subergorgia suberosa Antineoplastic Agents General Chemistry General Medicine Biology biology.organism_classification Anthozoa Biochemistry Gorgonian Cell Line Tumor Botany Tumor Cells Cultured Molecular Medicine Animals Humans Steroids Cancer cell lines Molecular Biology |
| Zdroj: | Chemistrybiodiversity. 9(2) |
| ISSN: | 1612-1880 |
| Popis: | Two new pentahydroxylated steroids, (3β,12β,16β,23E)-cholesta-5,23-diene-3,12,16,20,25-pentaol (1) and (3β,12β,16β)-cholesta-5,25(26)-diene-3,12,16,20,24-pentaol (2), were isolated from the EtOH extract of the South China Sea gorgonian Subergorgia suberosa. In addition, four known steroids were detected. The structures of these compounds were established by spectroscopic methods and comparison of their data with those of the related known compounds. In addition, the cyctotoxicities of the compounds were evaluated against selected cancer cell lines. |
| Databáze: | OpenAIRE |
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