Roux-Y Gastric Bypass and Sleeve Gastrectomy directly change gut microbiota composition independent of surgery type
| Autor: | Fernanda L. Paganelli, Malbert R. C. Rogers, James A. Groot, Danielle Adriaans, Marc J. M. Bonten, Roos-Marijn Berbers, Rob J. L. Willems, Misha Luyer, Helen L. Leavis, C. Marijn Hazelbag, Hae-Won Uh, Ad C. Fluit, Antoni P. A. Hendrickx, Marco C. Viveen |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Sleeve gastrectomy Rikenellaceae medicine.medical_treatment Gastric Bypass Bariatric Surgery lcsh:Medicine Gut flora Article 03 medical and health sciences 0302 clinical medicine Gastrectomy Weight loss Weight Loss medicine Journal Article Humans Obesity lcsh:Science General Multidisciplinary biology business.industry lcsh:R Middle Aged biology.organism_classification Streptococcaceae Gastrointestinal Microbiome Surgery Bifidobacteriaceae 030104 developmental biology Female lcsh:Q Composition (visual arts) Microbiome medicine.symptom business Roux y gastric bypass 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019) Scientific Reports, 9(1). Nature Publishing Group Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | Bariatric surgery in morbid obesity, either through sleeve gastrectomy (SG) or Roux-Y gastric bypass (RYGB), leads to sustainable weight loss, improvement of metabolic disorders and changes in intestinal microbiota. Yet, the relationship between changes in gut microbiota, weight loss and surgical procedure remains incompletely understood. We determined temporal changes in microbiota composition in 45 obese patients undergoing crash diet followed by SG (n = 22) or RYGB (n = 23). Intestinal microbiota composition was determined before intervention (baseline, S1), 2 weeks after crash diet (S2), and 1 week (S3), 3 months (S4) and 6 months (S5) after surgery. Relative to S1, the microbial diversity index declined at S2 and S3 (p p p |
| Databáze: | OpenAIRE |
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