Central nervous system localisation of chronic lymphocytic leukaemia, description of two very distinct cases and a review of the literature
| Autor: | Saskia K. Klein, Rob C M van Kruijsdijk, Josanne S. de Maar, Nyanza K. L. M. Timmers |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Pathology Chronic lymphocytic leukaemia Neurological localisation Central nervous system Apathy Vision Disorders Neurological symptoms Central Nervous System Neoplasms Diagnosis Differential 03 medical and health sciences 0302 clinical medicine immune system diseases Internal medicine hemic and lymphatic diseases medicine Humans In patient Cognitive Dysfunction Stage (cooking) neoplasms Aged Aged 80 and over Hematology Lymphocytic leukaemia business.industry Leptomeningeal CLL Delirium General Medicine Leukemia Lymphocytic Chronic B-Cell medicine.anatomical_structure 030220 oncology & carcinogenesis Female Original Article business CLL 030215 immunology |
| Zdroj: | Annals of Hematology |
| ISSN: | 1432-0584 |
| Popis: | Central nervous system (CNS) localisation of chronic lymphocytic leukaemia (CLL) can induce various neurological symptoms. Unfamiliarity with this manifestation causes diagnostic delay. We present two cases of leptomeningeal CLL. These cases and our literature review emphasise that CNS localisation of CLL should be considered in patients with any neurological symptom, irrespectively of the stage and systemic activity of CLL. Electronic supplementary material The online version of this article (10.1007/s00277-018-3329-2) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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