Synthetic Elastography Using B-Mode Ultrasound Through a Deep Fully Convolutional Neural Network

Autor: Massimo Mischi, Pedro Henrique de Marqui Moraes, Hessel Wijkstra, Georg Salomon, Christophe K. Mannaerts, R.R. Wildeboer, Maria Cristina Chammas, R.J.G. van Sloun
Přispěvatelé: Graduate School, APH - Quality of Care, Urology, APH - Personalized Medicine, Center for Care & Cure Technology Eindhoven, Biomedical Diagnostics Lab, Signal Processing Systems, EAISI Health
Rok vydání: 2020
Předmět:
FOS: Computer and information sciences
Scanner
Acoustics and Ultrasonics
Computer science
Computer Vision and Pattern Recognition (cs.CV)
shear-wave elastography (SWE)
Computer Science - Computer Vision and Pattern Recognition
Thyroid Gland
SDG 3 – Goede gezondheid en welzijn
Convolutional neural network
030218 nuclear medicine & medical imaging
B-mode ultrasound
03 medical and health sciences
0302 clinical medicine
Deep Learning
SDG 3 - Good Health and Well-being
convolutional neural networks
FOS: Electrical engineering
electronic engineering
information engineering

medicine
Image Processing
Computer-Assisted

Humans
Electrical and Electronic Engineering
Acoustic radiation force
Instrumentation
medicine.diagnostic_test
business.industry
B mode ultrasound
Deep learning
Image and Video Processing (eess.IV)
Ultrasound
Pattern recognition
Electrical Engineering and Systems Science - Image and Video Processing
Visualization
030220 oncology & carcinogenesis
Elasticity Imaging Techniques
Elastography
Artificial intelligence
business
Zdroj: IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 67(12):9046008, 2640-2648. Institute of Electrical and Electronics Engineers Inc.
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 67(12):9046008, 2640-2648. Institute of Electrical and Electronics Engineers
ISSN: 1525-8955
0885-3010
Popis: Shear-wave elastography (SWE) permits local estimation of tissue elasticity, an important imaging marker in biomedicine. This recently-developed, advanced technique assesses the speed of a laterally-travelling shear wave after an acoustic radiation force "push" to estimate local Young's moduli in an operator-independent fashion. In this work, we show how synthetic SWE (sSWE) images can be generated based on conventional B-mode imaging through deep learning. Using side-by-side-view B-mode/SWE images collected in 50 patients with prostate cancer, we show that sSWE images with a pixel-wise mean absolute error of 4.5+/-0.96 kPa with regard to the original SWE can be generated. Visualization of high-level feature levels through t-Distributed Stochastic Neighbor Embedding reveals substantial overlap between data from two different scanners. Qualitatively, we examined the use of the sSWE methodology for B-mode images obtained with a scanner without SWE functionality. We also examined the use of this type of network in elasticity imaging in the thyroid. Limitations of the technique reside in the fact that networks have to be retrained for different organs, and that the method requires standardization of the imaging settings and procedure. Future research will be aimed at development of sSWE as an elasticity-related tissue typing strategy that is solely based on B-mode ultrasound acquisition, and the examination of its clinical utility.
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Databáze: OpenAIRE