HIV incidence and risk contributing factors among men who have sex with men in Benin: A prospective cohort study

Autor: Septime Hessou, Michel Alary, Codjo Djignefa Djade, Michel Boko, Alphonse Biaou, Clément Ahoussinou, Yolaine Glèlè-Ahanhanzo, Christian R. Johnson, Rhéda Adekpedjou
Rok vydání: 2019
Předmět:
Male
Safe Sex
RNA viruses
Epidemiology
Physiology
Social Stigma
Psychological intervention
Social Sciences
HIV Infections
Pathology and Laboratory Medicine
law.invention
Men who have sex with men
Condoms
Cohort Studies
Geographical Locations
Sexual and Gender Minorities
0302 clinical medicine
Immunodeficiency Viruses
law
Risk Factors
Reproductive Physiology
Copulation
Medicine
Benin
Psychology
030212 general & internal medicine
Prospective Studies
Prospective cohort study
Univariate analysis
education.field_of_study
Multidisciplinary
Incidence
Age Factors
virus diseases
Social Discrimination
Homosexuality
HIV epidemiology
Medical Microbiology
Research Design
Viral Pathogens
Viruses
Infectious diseases
Pathogens
0305 other medical science
Cohort study
Research Article
Adult
Science
Population
Men WHO Have Sex with Men
Viral diseases
Research and Analysis Methods
Microbiology
03 medical and health sciences
Young Adult
Risk-Taking
Condom
Retroviruses
Humans
Sexual Identity
education
Microbial Pathogens
Medicine and health sciences
030505 public health
business.industry
Proportional hazards model
Lentivirus
Organisms
Biology and Life Sciences
HIV
Socioeconomic Factors
People and Places
Africa
Population Groupings
business
Demography
Sexuality Groupings
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0233624 (2020)
ISSN: 1932-6203
Popis: Men who have sex with Men (MSM) are a key population in the transmission of Human Immunodeficiency Virus (HIV) infection. In Benin, there is a lack of strategic information to offer appropriate interventions for these populations who live hidden due to their stigmatization and discrimination. The objective is to identify contributing factors that affect HIV incidence in the MSM population. Study of a prospective cohort of 358 HIV-negative MSM, aged 18 years and over, reporting having had at least one oral or anal relationship with another man during the last 12 months, prior to recruitment. The monitoring lasted 30 months with a follow-up visit every six months. Univariate analyses and a Cox proportional hazards multivariate regression were used to examine the association between bio-behavioral, socio-demographic and knowledge-related characteristics with HIV incidence. The retention rate for the follow-up of the 358 participants was 94.5%. On the 813.5 person-years of follow-up, 48 seroconversions with an HIV incidence of 5.91 per 100 person-years were observed (95% CI: 4.46-7.85). Factors associated with the high risk of HIV were age (HR = 0.4; 95% CI: 0.2-0.8), living in couple (HR = 0.5 95% CI: 0.2-0.96) and the lack of condom systematic use with a male partner during high-risk sex (HR = 3.9; 95% CI: 1.4-11.1). HIV incidence is high within MSM population and particularly among young people. Targeted, suitable and cost-effective interventions for the delivery of the combination prevention package in an environment free of stigma and discrimination are necessary and vital for reaching the 90x90x90 target.
Databáze: OpenAIRE
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