Use of In Vivo Real-Time Optical Imaging for Esophageal Neoplasia
| Autor: | Nadhi Thekkek, Peter M. Vila, Rebecca Richards-Kortum, Sharmila Anandasabapathy |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Pathology Esophageal Neoplasms Adenocarcinoma Article Barrett Esophagus Endoscopic imaging Optical imaging In vivo medicine Medical imaging Humans Esophagus Microscopy Confocal medicine.diagnostic_test business.industry Cancer General Medicine Image Enhancement medicine.disease Endoscopy medicine.anatomical_structure Barrett's esophagus Esophagoscopy Radiology business Precancerous Conditions Tomography Optical Coherence |
| Zdroj: | Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine. 78:894-904 |
| ISSN: | 0027-2507 |
| DOI: | 10.1002/msj.20304 |
| Popis: | Esophageal adenocarcinoma carries a poor prognosis, as it typically presents at a late stage. Thus, a major research priority is the development of novel diagnostic-imaging strategies that can detect neoplastic lesions earlier and more accurately than current techniques. Advances in optical imaging allow clinicians to obtain real-time histopathologic information with instant visualization of cellular architecture and the potential to identify neoplastic tissue. The various endoscopic imaging modalities for esophageal neoplasia can be grouped into 2 major categories: (1) wide-field imaging, a comparatively lower-resolution view for imaging larger surface areas, and (2) high-resolution imaging, which allows individual cells to be visualized. This review will provide an overview of the various forms of real-time optical imaging in the diagnosis and management of Barrett's esophagus and esophageal adenocarcinoma. Mt Sinai J Med 78:894–904, 2011. © 2011 Mount Sinai School of Medicine |
| Databáze: | OpenAIRE |
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