Silver-coated nylon fiber as an antibacterial agent
| Autor: | P C MacKeen, W Snipes, S C Warner, Stanley Person, S E Stevens |
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| Rok vydání: | 1987 |
| Předmět: |
Tris
Staphylococcus aureus Silver Kinetics Buffer (optical fiber) Streptococcus agalactiae chemistry.chemical_compound Escherichia coli Staphylococcus epidermidis Organic chemistry Pharmacology (medical) Fiber Antibacterial agent Pharmacology biology Extraction (chemistry) Temperature biology.organism_classification Lactococcus lactis Klebsiella pneumoniae Nylons Silver nitrate Infectious Diseases chemistry Delayed-Action Preparations Pseudomonas aeruginosa Silver Nitrate Bacteria Research Article Nuclear chemistry |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 31:93-99 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.31.1.93 |
| Popis: | A blend of nylon fiber and silver-coated nylon fiber (the latter known as X-static) was used in these experiments. This fiber was bactericidal when bacteria were exposed to it directly or to an extract derived from its prior incubation in salt solution. At ambient temperatures, a rapid exponential decrease of survival occurred, usually after a delay of approximately 1 h. The rate of killing (decrease of survival) increased with an increase in X-static percentage of the fiber blend, temperature of fiber extraction, concentration of Tris buffer present during extraction, and temperature at which bacteria were exposed to the extract. When bacteria were exposed to the extract at 37 degrees C as opposed to ambient temperature, there was no delay in onset of killing. Escherichia coli was generally the indicator organism tested, but comparable results were also found for Pseudomonas, Klebsiella, Staphylococcus, and Streptococcus species. The rate of killing increased with increasing silver ion concentration of the fiber extract, as determined through atomic absorption spectrophotometry. The rate of killing was greater and the onset was earlier with an extract containing silver ions from fiber than with a salt solution containing the same concentration of silver ions from silver nitrate. Studies of the kinetics of ion release suggested that X-static may be an effective, sustained-release antibacterial agent. |
| Databáze: | OpenAIRE |
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