A comprehensive evaluation of the chemical profiles and biological properties of six geophytes from Turkey: Sources of bioactive compounds for novel nutraceuticals
| Autor: | Monica Gallo, Devina Lobine, Gokhan Zengin, Kouadio Ibrahime Sinan, Mustafa Yilmaz, Gunes Ak, Evren Yildiztugay, Mohamad Fawzi Mahomoodally, Souheir Bensari, Domenico Montesano, Rayene Ouelbani |
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| Přispěvatelé: | Dicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümü, Yılmaz, Mustafa Abdullah, Fawzi Mahomoodally, M., Zengin, G., Ibrahime Sinan, K., Yildiztugay, E., Lobine, D., Ouelbani, R., Bensari, S., Ak, G., Abdullah Yilmaz, M., Gallo, M., Montesano, D. |
| Rok vydání: | 2020 |
| Předmět: |
Turkey
030309 nutrition & dietetics Flavonoid Phytochemical Iris stenophylla 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology Chlorogenic acid Tandem Mass Spectrometry chemistry.chemical_classification 0303 health sciences biology Traditional medicine Chemistry Plant Extracts Amylase 04 agricultural and veterinary sciences Quinic acid Cholinesterase biology.organism_classification 040401 food science Bulb Phenolic Polyphenol Dietary Supplements Nutraceutical Muscari neglectum Antioxidant Food Science Chromatography Liquid |
| Zdroj: | Food research international (Ottawa, Ont.). 140 |
| ISSN: | 1873-7145 0006-2316 |
| Popis: | WOS:000623164500003 PMID: 33648291 Geophytes are gaining interest as sources of natural ingredients in nutraceutical and pharmaceutical area. In this sense, six bulbous plant species from Turkey are investigated, namely Hyacinthella campanulata K.Perss. & Wendelbo, Muscari neglectum Guss. ex Ten., Tulipa humilis herb., Iris stenophylla Hausskn. ex Baker, Galanthus elwesii Hook. f. and Crocus danfordiae Maw. with the aim to highlight their chemical compositions and biological properties. Polyphenolic profiles of the different plant parts (flower, bulb and leaf) of the six genotypes were evaluated using colorimetric methods as well LC-MS/MS. The antioxidant properties and enzymes inhibitory potential (alpha-amylase, alpha-glucosidase, tyrosinase and cholinesterases) of the extracts were determined. Overall, highest total phenolic content and total flavonoid content were observed in the leaf extracts of the studied species, except for M. neglectum (flower extract) and T. humilis (flower extract). LC-MS/MS analysis revealed the abundance of some phenolic compounds including quinic acid, hesperidin and chlorogenic acid in selective extracts. The extracts showed significant antioxidant potentials, with leaf extract of the I. stenophylla being more potent, which is linked to its high phenolic contents. All the extracts displayed notable anti-acetylcholinesterase (1.77 - 2.53 mg GALAE/g) and tyrosinase (54.9-67.20 mg KAE/g). Selective extracts have showed activity against butyrylcholinesterase, with bulb extract of M. neglectum (2.99 mg GALAE/g), I. stenophylla (2.53 mg GALAE/g) and G. elwesii (2.52 mg GALAE/g) showing highest activity. Modest activity was observed against alpha-amylase and alpha-glucosidase. The experimental data gathered herein is the first report on the phytochemical and biological attributes of these bulbous plant species which project them as potential sources of biologically active compounds for phytomedicines and nutraceuticals development. |
| Databáze: | OpenAIRE |
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