Learning from the Slime Mold: Dictyostelium and Human Disease
| Autor: | Charles L. Saxe |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
food.ingredient
Protozoan Proteins macromolecular substances Dictyostelium discoideum Amoeba (genus) food Human disease Slime mold Genetics Animals Humans Dictyostelium Genetics(clinical) Genetics (clinical) Communication Models Genetic biology Phylum business.industry Wiscott-Aldrich syndrome Actin cytoskeleton fungi Proteins Motility DNA Restriction Enzymes biology.organism_classification Actins Cell aggregation Wiskott-Aldrich Syndrome Wiskott-Aldrich Syndrome Protein Family Multigene Family business Wiskott-Aldrich Syndrome Protein Research Article Signal Transduction |
| Zdroj: | The American Journal of Human Genetics. 65(1):25-30 |
| ISSN: | 0002-9297 |
| DOI: | 10.1086/302476 |
| Popis: | When readers of this Journal think about Dictyostelium—rarely, if at all, I suspect—they may conjure up dim memories either of college laboratory demonstrations involving cell aggregation and cAMP or of watching the cells develop into tiny fruiting bodies made of spores and stalks. Yeasts and several invertebrate or vertebrate model systems are widely known for their contributions to our understanding of human disease, but Dictyostelium is seldom included in this list. Quietly, over the last few years, however, research on this social amoeba has revealed some common cellular characteristics shared across diverse phyla. |
| Databáze: | OpenAIRE |
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