Regioisomers Salviprolin A and B, Unprecedented Rosmarinic Acid Conjugated Dinorditerpenoids from Salvia przewalskii Maxim
| Autor: | Meifang Wu, Jielang Lu, Xiangdong Su, Shujie Jia, Xin He, Yongbo Xue, Hui Xing, Shuna Liu, Yichuang Wu, Yuyang Zhou |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
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4-benzodioxane rosmarinic acid food.ingredient Pharmaceutical Science Organic chemistry Salvia Conjugated system Depsides Plant Roots Article Analytical Chemistry chemistry.chemical_compound food QD241-441 Salvia przewalskii Maxim Cell Line Tumor Neoplasms Drug Discovery Structural isomer Humans Physical and Theoretical Chemistry Salvia przewalskii Medicinal plants Lamiaceae Plants Medicinal biology Traditional medicine Rosmarinic acid biology.organism_classification Antineoplastic Agents Phytogenic chemistry Chemistry (miscellaneous) dinorditerpenoids Cinnamates Herb Molecular Medicine Diterpenes |
| Zdroj: | Molecules Volume 26 Issue 22 Molecules, Vol 26, Iss 6955, p 6955 (2021) |
| ISSN: | 1420-3049 |
| Popis: | Salvia przewalskii Maxim is a perennial plant from the genus Salvia (family Lamiaceae). The roots of S. przewalskii were long used as a traditional herb to treat blood circulation related illnesses in China. As part of our continuing interest in polycyclic natural products from medicinal plants, two unprecedented adducts comprised of a dinor-diterpenoid and a 9′-nor-rosmarinic acid derivative, linked by a 1,4-benzodioxane motif (1 and 2), were isolated from the roots of S. przewalskii. Their structures were established by extensive spectroscopic approaches including 1D, 2D NMR, and HRFABMS. Their cytotoxic activities against five human tumor cell lines were evaluated. |
| Databáze: | OpenAIRE |
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