Supplementary Data from Microenvironmental Activation of Nrf2 Restricts the Progression of Nrf2-Activated Malignant Tumors

Autor: Masayuki Yamamoto, Hozumi Motohashi, Hiroshi Kitamura, Harit Panda, Mikiko Suzuki, Ayumi Kuga, Makiko Hayashi
Rok vydání: 2023
DOI: 10.1158/0008-5472.22423673
Popis: Figure S1: Expression of Keap1 and Nqo1 in Keap1WT/WT, Keap1FB/FB and Keap1FA/FA mouse tissues; Figure S2: Analyses of tumor-bearing mouse cohorts; Figure S3: Origins of tumor cells in Kras::Keap1WT/WT, Kras::Keap1FB/FB and Kras::Keap1FA/FA lungs; Figure S4. Analyses of tumor-bearing Kras::Keap1FA/FA mouse cohorts that received Keap1FA/FA, Keap1WT/WT or Nrf2-/- bone marrows; Table S1: Primers and probes for qRT-PCR analyses; Table S2: Primers for analyses of recombination efficiency; Supplementary Materials and Methods (Establishment of mouse embryonic fibroblasts (MEFs), Validation of the recombination efficiency, Immunoblot analyses, Histology and Immunohistochemistry, Flow cytometry, and isolation of CD8+ T cells in tumor-bearing lungs)
Databáze: OpenAIRE