Strong bonding of corneal incisions using a noncontact fiber-optic laser soldering method
| Autor: | Ilana Nisky, Mickey Harlev, Doron Ofer, Svetlana Basov, Yair Dankner, David Varssano, Abraham Katzir, Irina S. Barequet, Max Platkov, Marcel Rattunde, Mordechai Rosner, Joachim Wagner, Ilan Gabay |
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| Přispěvatelé: | Publica |
| Rok vydání: | 2019 |
| Předmět: |
Paper
optical fibers Materials science genetic structures Swine medicine.medical_treatment Biomedical Engineering 01 natural sciences law.invention 010309 optics Biomaterials Optical coherence tomography law cornea Cornea 0103 physical sciences medicine Animals Fiber Optic Technology Laser bonding albumin Wound Healing medicine.diagnostic_test Laser beam welding Cataract surgery Laser Sutureless Surgical Procedures eye diseases Atomic and Molecular Physics and Optics laser soldering Electronic Optical and Magnetic Materials Transplantation laser bonding medicine.anatomical_structure Soldering infrared Laser Therapy sense organs Therapeutic Biomedical engineering |
| Zdroj: | Journal of Biomedical Optics |
| ISSN: | 1083-3668 |
| DOI: | 10.1117/1.jbo.24.12.128002 |
| Popis: | Suturing of corneal incisions requires significant skill. We demonstrate a noncontact method that will simplify the bonding process. 5-mm-long penetrating vertical and slanted incisions were made in corneas of eyes, extracted from dead piglets. A fiber-optic laser system was used for laser soldering of the incisions, under close temperature control, using albumin solder. The burst-pressure PB immediately after the soldering was found to be PB ≈92 and 875 mmHg, for vertical and slanted incisions, respectively. PB=875 mmHg is an exceptionally high figure, ≈10 times the clinically acceptable value for sutured incisions. Laser soldering was then performed on penetrating incisions made in the corneas of live healthy piglets, of weight ≈10 Kg. After a healing period,the eyes were extracted,and the corneas were examined by histopathology and by optical coherence tomography. Our method immediately generated watertight and strong bonding without noticeable corneal shape distortion. These results would be beneficial for cataract surgery and for corneal transplantations. The fiber-optic system makes it much easier to bond corneal incisions. In the future, laser soldering could be automated and efficiently used by less experienced surgeons, thereby reducing the workload on the experienced ones. |
| Databáze: | OpenAIRE |
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