Seroprevalence of Tularemia in Rural Azerbaijan
| Autor: | Saleh Piraliyev, Huseyn Hajiyev, Maqsud Qasimov, Danielle V Clark, Afag Aslanova, Matthew J. Hepburn, Afrail Ismailov, Tahir Nuriyev, Esmiralda Seyidova, Sevinj Bakhishova, Amanda K. Debes, Ayten Hajiyeva, Sadigulla Bagirov |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Rural Population Azerbaijan Adolescent Climate Rodentia Signs and symptoms Tick Microbiology Asymptomatic Tularemia Ticks Risk Factors Seroepidemiologic Studies Virology Animals Humans Medicine Seroprevalence Risk factor Francisella tularensis Aged biology business.industry Middle Aged medicine.disease biology.organism_classification Antibodies Bacterial Geographic distribution Infectious Diseases Immunoglobulin G Asymptomatic Diseases Immunology Arachnid Vectors Female medicine.symptom business Demography |
| Zdroj: | Vector-Borne and Zoonotic Diseases. 12:558-563 |
| ISSN: | 1557-7759 1530-3667 |
| DOI: | 10.1089/vbz.2010.0081 |
| Popis: | A representative, two-stage probability sampling design was used to select 40 villages in northern Azerbaijan with populations of500 people to screen for evidence of prior infection with Francisella tularensis. Informed consent was provided, and samples were obtained from 796 volunteers and tested for the presence of immunoglobulin G antibodies using enzyme-linked immunosorbent assay. F. tularensis seropositivity was prevalent (15.5% of volunteers), but there was minimal reporting of signs and symptoms consistent with clinical tularemia, suggesting that mild or asymptomatic infection commonly occurs. Frequently seeing rodents around the home was a risk factor for seropositivity (POR = 1.6, p = 0.03), controlling for age and gender. Geospatial analysis identified associations between village-level tularemia prevalence and suitable tick habitats, annual rainfall, precipitation in the driest quarter, and altitude. This study contributes to the growing understanding of the geographic distribution of tularemia and provides further information on the climatic and landscape conditions that increased the potential for exposure to this pathogen. The potential occurrence of asymptomatic or mild F. tularensis infection warrants further study. |
| Databáze: | OpenAIRE |
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