| Autor: |
Steven P. Petrou, Paul R. Young, Michael J. Wehle, Melinda K. Knight, Robert Marino, Raul O. Parra, Gregory A. Broderick, Todd C. Igel |
| Rok vydání: |
2001 |
| Předmět: |
|
| Zdroj: |
The Journal of Urology. :1575-1579 |
| ISSN: |
0022-5347 |
| DOI: |
10.1097/00005392-200105000-00038 |
| Popis: |
Purpose: A negative biopsy result does not necessarily equate with cancer in specific high risk groups. We describe an alternative systematic biopsy technique for evaluating this subgroup of patients.Materials and Methods: From March 1997 to May 1999 a total of 88 men underwent systematic ultrasound guided biopsy using the transperineal template technique. All patients had undergone at least 1 and 75 (85%) had undergone 2 or more previous sets of biopsies. In addition, study inclusion required high risk parameters, including prostate specific antigen (PSA) velocity greater than 0.75 ng./ml., PSA greater than 10 ng./ml. or previous prostatic intraepithelial neoplasia on biopsy, and/or atypical small cell acinar proliferation.Results: Cancer was identified in 38 of the 88 men (43%) in this high risk subgroup undergoing repeat biopsy. A mean of 15.1 previous biopsy cores had been obtained. The most common biopsy grade was 6 (range 4 to 9). Adenocarcinoma was identified in the transition zone area in 29 of 38... |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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