Evaluation of nucleotide derivatives and sugar nucleotide analogs as inhibitors of glycosyltransferases
Autor: | Ai-Hua Lu, Ole Hindsgaul, Monica Palcic, Kenji Osumi, Nobuya Kawauchi |
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Rok vydání: | 2003 |
Předmět: |
chemistry.chemical_classification
biology Nucleotides Glycosyltransferases General Medicine In Vitro Techniques Nucleotide sugar N-Acetylglucosaminyltransferases Uridine Diphosphate chemistry.chemical_compound Uridine diphosphate Kinetics Structure-Activity Relationship chemistry Biochemistry Glycosyltransferase biology.protein Uridine monophosphate Nucleotide Enzyme Inhibitors Sugar Uridine Monophosphate Nucleoside Nucleotide salvage |
Zdroj: | Nucleic acids symposium series. (44) |
ISSN: | 0261-3166 |
Popis: | The inhibition of glycosyltrans ferases was studied using uridine monophosphate derivatives and uridine diphosphate sugar analogs. Modification in the nucleoside portion caused selective inhibition of glycosyltransferases. |
Databáze: | OpenAIRE |
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