Clinical Significance of MRI and Pathological Features of Giant Cell Tumor of Bone Boundary
Autor: | Ling‐di Qin, Qing‐jiao Zhang, Xiao‐lin Shi, Xiao‐hong Liu, Zi‐ming Zhou, Xiao‐yi Ding, Chen Liang, Lei Jiang |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Curettage Young Adult 03 medical and health sciences 0302 clinical medicine Magnetic resonance imaging lcsh:Orthopedic surgery Medical imaging medicine Humans Orthopedics and Sports Medicine Clinical significance Pathological Retrospective Studies 030222 orthopedics Clinical Article Tibia medicine.diagnostic_test business.industry Femoral Neoplasms Margins of Excision medicine.disease Immunohistochemistry Giant cell tumor of bone lcsh:RD701-811 Orthopedic surgery Clinical Articles Female Surgery business Nuclear medicine 030217 neurology & neurosurgery Kappa Giant-cell tumor of bone |
Zdroj: | Orthopaedic Surgery, Vol 11, Iss 4, Pp 628-634 (2019) Orthopaedic Surgery |
ISSN: | 1757-7853 1757-7861 |
Popis: | Objective To find new clues to reduce postoperative recurrence after intralesional curettage by studying MRI and pathological features of giant tumor of bone (GCTB) boundaries. Methods A retrospective study was performed in the departments of orthopaedic surgery and medical imaging at our hospitals from January 2006 to August 2016. A total of 16 GCTB patients confirmed by pathology were asked to participate in the present study. The age range was from 18 to 44 years (9 women and 7 men). All patients underwent MRI examination. All patients underwent en bloc resection and complete postoperative tumor segments were obtained. Five specimens were obtained randomly at the place of the segments where the GCTB boundary showed different types on MRI. Ordinary HE staining was used for all specimens and we measured the depth of local tumor cell infiltration (240 measurements). Results were expressed as means ± standard deviation. Statistical analyses were carried out with one‐way ANOVA and the Student–Newman–Keuls test. P |
Databáze: | OpenAIRE |
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