Intramolecular catalytic Friedel-Crafts reactions with allenyl cations for the synthesis of quinolines and their analogues

Autor:	Seiki Saito, Takayuki Kudo, Toshiaki Aikawa, Shinobu Manabe, Teruhiko Ishikawa
Rok vydání:	2004
Předmět:	chemistry.chemical_compound chemistry Intramolecular force Organic Chemistry Quinoline Organic chemistry General Medicine Physical and Theoretical Chemistry Isoquinoline Biochemistry Medicinal chemistry Friedel–Crafts reaction Catalysis
Zdroj:	Organic letters. 6(14)
ISSN:	1523-7060
Popis:	[reaction: see text] This paper describes a novel method to synthesize a quinoline backbone by incorporating allenyl cations into a catalytic intramolecular Friedel-Crafts reaction. The initial products were isomerized and aromatized upon treatment with acid and base, respectively, to give quinolines. The basic concept also proved to be promising for 1-benzazepine, 1-benzazocine, or isoquinoline synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d7f3eb262d3c55037b2223da48a961 https://pubmed.ncbi.nlm.nih.gov/15228279 Zobrazit plný text záznamu