Quality of life in overweight (obese) and normal-weight women with polycystic ovary syndrome
| Autor: | Giovanni Lupoli, Giuseppe Cibelli, Giovanni Messina, Ines Villano, Roberta Lupoli, Marianna Cacciapuoti, Francesco Precenzano, Gelsy Arianna Lupoli, Anna Valenzano, Marcellino Monda, Fiorenzo Moscatelli, Antonietta Messina, Vincenzo Monda, Teresa Esposito, Annalisa Panico |
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| Přispěvatelé: | Panico, Annalisa, Messina, Giovanni, Lupoli, Gelsy Arianna, Lupoli, Roberta, Cacciapuoti, Marianna, Moscatelli, Fiorenzo, Esposito, Teresa, Villano, Ine, Valenzano, Anna, Monda, Vincenzo, Messina, Antonietta, Precenzano, Francesco, Cibelli, Giuseppe, Monda, Marcellino, Lupoli, Giovanni |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Health-related quality-of-life
Normal-weight Obesity Polycystic ovary syndrome Psychological disturbances medicine.medical_specialty endocrine system diseases Medicine (miscellaneous) Disease Overweight 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine medicine Psychological disturbance Pharmacology Toxicology and Pharmaceutics (miscellaneous) Original Research lcsh:R5-920 030219 obstetrics & reproductive medicine Genetic heterogeneity business.industry Health Policy nutritional and metabolic diseases Health-related-quality-of-life medicine.disease Polycystic ovary female genital diseases and pregnancy complications Endocrinology Normal weight Patient Preference and Adherence medicine.symptom lcsh:Medicine (General) business Body mass index 030217 neurology & neurosurgery Social Sciences (miscellaneous) Polycystic Ovary Syndrome |
| Zdroj: | Patient Preference and Adherence, Vol Volume 11, Pp 423-429 (2017) Patient preference and adherence |
| ISSN: | 1177-889X |
| Popis: | Annalisa Panico,1 Giovanni Messina,2,3 Gelsy Arianna Lupoli,1 Roberta Lupoli,1 Marianna Cacciapuoti,1 Fiorenzo Moscatelli,2 Teresa Esposito,3 Ines Villano,3 Anna Valenzano,2 Vincenzo Monda,3 Antonietta Messina,3 Francesco Precenzano,4 Giuseppe Cibelli,2 Marcellino Monda,3 Giovanni Lupoli1 1Department of Clinical Medicine and Surgery, University of Napoli Federico II, Naples, Italy; 2Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 3Department of Experimental Medicine, Second University of Naples, Naples, Italy; 4Department of Mental and Physical Health, and Preventive Medicine, Child and Adolescent Neuropsychiatry Unit, Second University of Naples, Naples, Italy Objective: Polycystic ovary syndrome (PCOS) is characterized by phenotypic heterogeneity and has a wide variety of consequences. Approximately half of women with PCOS are overweight or obese, and their obesity may be a contributing factor to PCOS pathogenesis through different mechanisms. The aim of this study was to evaluate if PCOS alone affects the patients’ quality of life and to what extent obesity contributes to worsen this disease. Design: To evaluate the impact of PCOS on health-related quality-of-life (HRQoL), 100 Mediterranean women with PCOS (group A), 50 with a body mass index (BMI) >25kg/m2 (group A1) and 50 with BMI 25 (A1) showed a significant and more marked reduction in scores, suggesting a lower quality of life, compared with controls (B) and with normal-weight PCOS patients (A2). Conclusion: PCOS is a complex disease that alone determines a deterioration of HRQoL. The innovative use of these psychometric questionnaires in this study, in particular the PCOS questionnaire, has highlighted that obesity has a negative effect on HRQoL. It follows that a weight decrease is associated to phenotypic spectrum improvement and relative decrement in psychological distress. Keywords: polycystic ovary syndrome, obesity, normal-weight, health-related quality-of-life, psychological disturbances |
| Databáze: | OpenAIRE |
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