Topoisomerase i inhibitors from theStreptomyces sp. strain KM86-9B isolated from a marine sponge
| Autor: | Kwang Sik Im, Hong Kum Lee, Jung-Hyun Lim, Deuk-Soo Lee, Jung Sun Kim, Jee H. Jung |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
biology
Strain (chemistry) Topoisomerase Fatty Acids Organic Chemistry Pharmacology toxicology Fractionation Chemical Fractionation Topoisomerase-I Inhibitor biology.organism_classification Streptomyces Porifera Microbiology Sponge Biochemistry Drug Discovery biology.protein Animals Molecular Medicine Topoisomerase I Inhibitors |
| Zdroj: | Archives of Pharmacal Research. 21:729-733 |
| ISSN: | 1976-3786 0253-6269 |
| Popis: | The crude extract of Streptomyces sp. strain KM86-9B, isolated from a marine sponge, displayed significant inhibition on topoisomerase I activity. Investigation of the causative components by bioactivity-directed fractionation resulted in the isolation of a series of iso- and anteiso-fatty acids. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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