Interaction of tetracycline with l-cysteine functionalized CdS quantum dots - Fundamentals and sensing application
| Autor: | K. Girish Kumar, Unni Sivasankaran, Sanu K. Anand, Ammu Rosin Jose |
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| Rok vydání: | 2018 |
| Předmět: |
Time Factors
Tetracycline Nanotechnology 02 engineering and technology Biosensing Techniques Pharmaceutical formulation 010402 general chemistry 01 natural sciences Analytical Chemistry Quantum Dots Spectroscopy Fourier Transform Infrared medicine Cysteine Instrumentation Spectroscopy Detection limit Quenching (fluorescence) Chemistry 021001 nanoscience & nanotechnology Atomic and Molecular Physics and Optics Carbon 0104 chemical sciences Spectrometry Fluorescence Quantum dot Tetracyclines Steady state (chemistry) Time-resolved spectroscopy 0210 nano-technology medicine.drug |
| Zdroj: | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 213 |
| ISSN: | 1873-3557 |
| Popis: | The present paper reports l -cysteine functionalized CdS quantum dots (QDs) as a simple and highly selective turn-off fluorescence sensor for the determination of tetracycline (TET). The unauthorized use of TET may pose serious health hazards in human beings and hence the detection and determination has become very essential. In this regard, we have developed a sensor that enable the quantification of TET in the range 6.00 × 10−4 M to 1.50 × 10−5 M with a limit of detection 7.78 × 10−6 M, under optimized conditions. Steady state and time resolved fluorescence spectroscopic studies were used for investigating the mechanism of quenching and was found to be a combination of static and dynamic processes. The analytical application of the proposed sensor was investigated in pharmaceutical formulation. |
| Databáze: | OpenAIRE |
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