Is extracorporeal shockwave lithotripsy a risk factor for the development of diabetes mellitus? A population-based study
| Autor: | Michael Ordon, Blayne Welk, Jason Y. Lee, Daniela Ghiculete, Kenneth T. Pace |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Urology medicine.medical_treatment Population 030232 urology & nephrology Lithotripsy Kidney Calculi 03 medical and health sciences 0302 clinical medicine Risk Factors Diabetes Mellitus Ureteroscopy medicine Humans Risk factor education Retrospective Studies education.field_of_study medicine.diagnostic_test business.industry Incidence Hazard ratio Middle Aged Survival Analysis Confidence interval 030220 oncology & carcinogenesis Cohort Female business Cohort study |
| Zdroj: | BJU International. 123:1048-1054 |
| ISSN: | 1464-4096 |
| Popis: | OBJECTIVE To determine if patients treated with extracorporeal shockwave lithotripsy (ESWL) are at a greater risk of developing diabetes mellitus (DM) than those treated with ureteroscopy (URS). PATIENTS AND METHODS A retrospective population-based cohort study was performed of all ESWL and URS stone treatments done in Ontario between January 1994 and March 2014, utilising linked encoded healthcare databases. The primary outcome was the development of DM >90 days after treatment. The Kaplan-Meier method was used for unadjusted survival analysis and multivariable analysis with Cox proportional hazards regression was used to assess the risk of DM between the ESWL and URS groups whilst controlling for age, gender, region of residence, income quintile, year of treatment, and comorbidity index. A sensitivity analysis with a subset of ESWL patients treated for left renal or proximal ureteric stones was completed. RESULTS We identified 106 963 patients who underwent ESWL or URS over the study period with a median follow-up of 6.6 years (ESWL 8.5 years, URS 5.6 years). Unadjusted survival analysis showed an increased risk of developing DM in the ESWL group compared to the URS group (P |
| Databáze: | OpenAIRE |
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