Trace-Water-Induced Competitive Coordination Synthesis and Functionalization of Porphyrinic Metal–Organic Framework Nanoparticles for Treatment of Hypoxic Tumors
| Autor: | Wang Jinghan, Yaoqing Hu, Xiao Wang, Shanqing Gao, Juewen Liu, Feng Bai, Yong Zhong |
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| Rok vydání: | 2021 |
| Předmět: |
Photosensitizing Agents
Chemistry Biochemistry (medical) Inorganic chemistry Biomedical Engineering Water Nanoparticle Oxides General Chemistry Biomaterials Trace (semiology) Manganese Compounds Neoplasms Tumor Microenvironment Humans Nanoparticles Surface modification Metal-organic framework Hypoxia Metal-Organic Frameworks |
| Zdroj: | ACS Applied Bio Materials. 4:7322-7331 |
| ISSN: | 2576-6422 |
| DOI: | 10.1021/acsabm.1c00852 |
| Popis: | Controlling the size and morphology of metal-organic frameworks (MOF) has received increasing research interest but remains a great challenge. In this work, we demonstrate a trace-water-induced competitive coordination procedure to controllably synthesize porphyrinic MOFs including needle-shaped nanomaterials, hollow nanotubes, and nanocubes, using 5,10,15,20-tetrakis(4-carboxyphenyl) porphyrin as organic linkers and Zr |
| Databáze: | OpenAIRE |
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