Surfactant-Assisted Synthesis of Polyvinylpyrrolidone-hydroxyapatite Composites as a Bone Filler
| Autor: | Masoumeh Meskinfam Langroudi, Masoud Giahi Saravani, Azita Nouri |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Filler (packaging)
Bone Regeneration Materials science Biocompatibility Biomedical Engineering Biophysics Biocompatible Materials Bioengineering 02 engineering and technology Materials testing 010402 general chemistry 01 natural sciences Nanocomposites Biomaterials Surface-Active Agents Pulmonary surfactant Materials Testing medicine Humans Composite material Cells Cultured Nanocomposite Tissue Engineering Polyvinylpyrrolidone Bone Cements Povidone General Medicine 021001 nanoscience & nanotechnology 0104 chemical sciences Durapatite Bone Substitutes 0210 nano-technology Inorganic nanoparticles medicine.drug |
| Zdroj: | Journal of Applied Biomaterials & Functional Materials. 15:e334-e340 |
| ISSN: | 2280-8000 |
| DOI: | 10.5301/jabfm.5000348 |
| Popis: | Background Different methods have been used to prepare bone-like composites from inorganic nanoparticles embedded in polymeric matrixes to obtain the properties and structures required for bone fillers. Methods Bone-like nano-hydroxyapatite (nHA) was synthesized using a biomimetic method, with polyvinylpyrrolidone (PVP) as template and sodium dodecyl sulfate (SDS) as surfactant. Results The results demonstrated the formation of HA composites and showed that polymer and surfactant as the polymer capsule can be properly used to control the size, shape, morphology and dispersion of HA crystals. All of the samples were bioactive due to their ability to form carbonate apatite and grow HA on their surface. The MTT assay showed that the samples were biocompatible. Conclusions Based on bioactivity and biocompatibility evaluations, the prepared composites can be considered as good candidates for bone filler applications. |
| Databáze: | OpenAIRE |
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