Evaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey: A nationwide cross-sectional study
| Autor: | Şükran Darcan, Rüveyde Bundak, Cengiz Kara, Halil Saglam, Ahmet Uçaktürk, Filiz Tutunculer, Aysegul Yuksel, Tolga Ünüvar, Şükrü Hatun, Huseyin Demirbilek, Abdullah Bereket, Ergun Cetinkaya, Enver Simsek, Damla Gökşen Şimşek, Cigdem Binay, Yaşar Cesur |
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| Přispěvatelé: | CESUR, Yaşar, Ondokuz Mayıs Üniversitesi, Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Endokrinolojisi Anabilim Dalı., Sağlam, Halil, C-7392-2019 |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Continuous infusion
Single drug dose Blood Glucose Male Pediatrics Turkey endocrine system diseases Cross-sectional study Endocrinology Diabetes and Metabolism medicine.medical_treatment Glucose blood level Comorbidity Prescription Turkey (republic) Insulin aspart 0302 clinical medicine Endocrinology Glycemic control immune system diseases Hemoglobin A glycosylated Prevalence Insulin Region 030212 general & internal medicine Child Children Endocrinology & metabolism Disease Management General Medicine Type 1 diabetes Child Preschool Insulin detemir Insulin lispro Female Sex ratio Treatment planning Celiac Disease Insulin Dependent Diabetes Mellitus Patient with Type 1 Diabetes Human Risk Adult medicine.medical_specialty Insulin glargine HbA1c Adolescent Insulin dependent diabetes mellitus 030209 endocrinology & metabolism Major clinical study Hypoglycemia Article A nationwide cross-sectional study- DIABETES RESEARCH AND CLINICAL PRACTICE cilt.119 ss.32-40 2016 [Hatun S. DEMIRBILEK H. DARCAN Ş. Yuksel A. Binay C. Simsek D. G. Kara C. CETINKAYA E. UNUVAR T. UCAKTURK A. et al. -Evaluation of therapeutics management patterns and glycemic control of pediatric type 1 diabetes mellitus patients in Turkey] Association 03 medical and health sciences Disease association Diabetes mellitus Dose response Internal Medicine medicine Humans Clinical evaluation Intensive care medicine Isophane insulin Glycemic Asthma Disease duration Glycated Hemoglobin business.industry Pig insulin Infant nutritional and metabolic diseases Glycosylated hemoglobin medicine.disease Drug effect Treatment Cross-Sectional Studies Diabetes Mellitus Type 1 Basal (medicine) Preschool child business Analysis |
| Popis: | Hatun, Sukru/0000-0003-1633-9570; Mengen, Eda/0000-0003-1597-8418; binay, cigdem/0000-0002-7749-8818; UCAKTURK, Seyit Ahmet/0000-0001-8666-4454 WOS: 000381646900004 PubMed: 27423071 Aims: To evaluate the management strategies, glycemic control and complications of pediatric type 1 diabetes mellitus (T1DM) patients in Turkey. Methods: Study included 498 patients with T1DM between the ages 1-18. Data provided from patients' hospital files were recorded on standard case report forms by applicant clinicians within the 3 months of data collection period between October 2012 and July 2013. Results: Mean age of patients was 11.3 +/- 3.8 years. Mean duration of DM was determined as 3.7 +/- 3.1 years. Majority of patients (85.5%) used basal/bolus injection (BBI), and 6.5% used continuous subcutaneous insulin infusion pump. Assessment of glycemic control based on HbA1c levels showed that 29.1% of patients had an HbA1c value 9%(75 mmol/mol). Hypoglycemia was reported in 145 (29.1%) patients and the number of severe hypoglycemic attacks in the last 3 months was 1.0 +/- 2.4. Taking into consideration the carbohydrate count and insulin correction dose and parents with high socioeconomic status was related to have better glycemic control. The most common comorbidities were Hashimoto's thyroiditis/hypothyroidism (6.2%) followed by celiac disease (3.8%), epilepsy(1.2%), and asthma(1.0%). Conclusions: BBI insulin therapy is widely used among pediatric T1DM patients in Turkey. However, despite improvements in treatment facilities and diabetic care, glycemic control is not at a satisfactory level. Therefore, new and comprehensive initiatives require for pediatric T1DM patients with poor glycemic control. Promoting use of carbohydrate count and insulin correction doses may improve the glycemic control of pediatric T1DM in Turkey. (C) 2016 Elsevier Ireland Ltd. All rights reserved. Sanofi Study was funded by Sanofi. |
| Databáze: | OpenAIRE |
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