Effects of Qigong Exercise on Non-Motor Symptoms and Inflammatory Status in Parkinson’s Disease: A Protocol for a Randomized Controlled Trial
| Autor: | Wen Liu, Irina V. Smirnova, Kelly E. Lyons, Caio V.M. Sarmento, Yvonne Colgrove, Sanghee Moon, Sue M. Lai |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Parkinson's disease medicine.medical_treatment lcsh:Medicine Disease law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Quality of life law Protocol medicine Cognitive decline General Environmental Science Sleep disorder Rehabilitation business.industry Qigong lcsh:R General Engineering mind-body therapies medicine.disease cytokines 3. Good health 030220 oncology & carcinogenesis randomized controlled trial Parkinson’s disease Physical therapy General Earth and Planetary Sciences Anxiety medicine.symptom business human activities 030217 neurology & neurosurgery |
| Zdroj: | Medicines Medicines, Vol 6, Iss 1, p 13 (2019) |
| ISSN: | 2305-6320 |
| DOI: | 10.3390/medicines6010013 |
| Popis: | Background: Non-motor symptoms such as sleep disturbance, cognitive decline, fatigue, anxiety, and depression in Parkinson’s disease (PD) impact quality of life. Increased levels of pro-inflammatory cytokines in individuals with PD have been reported, which may contribute to non-motor symptoms. A mind-body exercise, Qigong, has demonstrated benefits across different medical conditions. However, a lack of evidence causes clinicians and patients to be uncertain about the effects of Qigong in individuals with PD. This study will examine the effects of Qigong on non-motor symptoms and inflammatory status in individuals with PD. Methods: Sixty individuals with PD will be recruited. Qigong and sham Qigong group (n = 30 for each) will receive a 12-week intervention. Participants will practice their assigned exercise at home (2×/day) and attend routinely group exercise meetings. Results: Clinical questionnaires and neuropsychological tests will measure non-motor symptoms including sleep quality (primary outcome). Biomarker assays will measure inflammatory status. A two-way mixed-design analysis of variance (ANOVA) will be utilized. Conclusions: This study may generate evidence for the benefits of Qigong on non-motor symptoms of PD and the effect on inflammatory status. Findings may lead to the development of a novel, safe, and cost-effective rehabilitation approach for individuals with PD. |
| Databáze: | OpenAIRE |
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