Thiamine hydrochloride as a recyclable organocatalyst for the efficient and chemoselective N-tert-butyloxycarbonylation of amines

Autor:	Dnyaneshwar N. Garad, Nitin M. Thorat, Dattatraya Ukale, Ajit P. Ingale, Sandeep V. Shinde
Rok vydání:	2021
Předmět:	chemistry.chemical_compound Chemistry Hydrochloride Organic Chemistry Thiamine Hydrochloride Organic chemistry
Zdroj:	Synthetic Communications. 51:3791-3804
ISSN:	1532-2432 0039-7911
DOI:	10.1080/00397911.2021.1994998
Popis:	Thiamin hydrochloride promoted highly efficient and ecofriendly approach has been described for the chemoselective N-tert-butyloxycarbonylation of amines under solvent-free conditions at ambient temperature. The demonstrated approach has been applicable for the N-Boc protection of variety of aliphatic, aryl, heteroaryl amines. The chemoselective protection of amino group occurs in chiral amines and amino alcohol without racemization in high yield. Thiamin hydrochloride is stable, economical, easy to handle and environmentally friendly.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0af502a96d1d3592301cc114508f5db https://doi.org/10.1080/00397911.2021.1994998 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.