Effects of chlordiazepoxide, oxazepam, chlorpromazine, andd-Amphetamine on sexual responses in male and female hamsters
| Autor: | Robert F. Daily, Carol Sue Carter, Russell C. Leaf |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Male
medicine.medical_specialty Dextroamphetamine Lordosis Chlorpromazine Chlordiazepoxide Sexual Behavior Animal Cricetinae Internal medicine medicine Animals Amphetamine Pharmacology Estrous cycle Dose-Response Relationship Drug biology Oxazepam business.industry biology.organism_classification medicine.disease Endocrinology Sexual behavior Depression Chemical Female business Injections Intraperitoneal Mesocricetus medicine.drug |
| Zdroj: | Psychopharmacology. 55:195-201 |
| ISSN: | 1432-2072 0033-3158 |
| DOI: | 10.1007/bf01457858 |
| Popis: | The acute effects on sexual behavior of oxazepam (16--64 mg/kg), chlordiazepoxide (8--64 mg/kg), chlorpromazine (2--8 mg/kg), and d-amphetamine (0.8--3.2 mg/kg) were examined in intact male and female golden hamsters (Mesocricetus auratus). Intraperitoneal injections were given 45 min before the first behavioral test. In 10-min tests, lordosis was observed in estrous females both before and after copulation, and mounts, intromissions, and ejaculations were observed in males. Dose-response related decrements in male sexual behavior were observed following chlorpromazine and chlordiazepoxide. All dose levels of oxazepam depressed male sexual behavior. The highest dose of chlordiazepoxide and oxazepam attenuated the onset of female sexual behavior, and all dose levels reduced postcopulatory lordosis durations. Amphetamine did not interrupt either male or female sexual behavior, and chlorpromazine disrupted male but not female behavior. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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