Supplemental Figure 3 from Histone Deacetylase Inhibition Has Targeted Clinical Benefit in ARID1A-Mutated Advanced Urothelial Carcinoma

Autor: Sunil Sharma, Joshua D. Schiffman, Bradley R. Cairns, William T. Lowrance, John M. O’Shea, Brian Dalley, Lisa M. Pappas, Alexis Weston, Andrew Butterfield, Timothy J. Parnell, Daniel J. Albertson, Sumati Gupta
Rok vydání: 2023
DOI: 10.1158/1535-7163.22504722
Popis: Heat map of top 50 genes affected in HT1197 cells when treated with panobinostat at 48 hours log2 gene expression change(HT1197 A-B and C represent control replicates, HT1197 Pano A, B, C represent treated replicates). For the cell lines with replicates, statistically significant genes were identified with a FDR of 2 fold. Plot was generated with R using median-centered regularized log2 values.
Databáze: OpenAIRE