Whole-tumor histogram analysis of DWI and QSI for differentiating between meningioma and schwannoma: a pilot study
| Autor: | Masashi Yasuike, Koji Sakai, Jun Tazoe, Kentaro Akazawa, Kei Yamada, Hitomi Nagano |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Percentile Pilot Projects Schwannoma 030218 nuclear medicine & medical imaging Diagnosis Differential Meningioma 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Histogram Image Interpretation Computer-Assisted Humans Effective diffusion coefficient Medicine Radiology Nuclear Medicine and imaging Retrospective Studies Receiver operating characteristic Brain Neoplasms business.industry Area under the curve Reproducibility of Results Middle Aged medicine.disease Magnetic Resonance Imaging Diffusion Magnetic Resonance Imaging ROC Curve Area Under Curve 030220 oncology & carcinogenesis Kurtosis Female business Nuclear medicine Neurilemmoma |
| Zdroj: | Japanese Journal of Radiology. 37:694-700 |
| ISSN: | 1867-108X 1867-1071 |
| DOI: | 10.1007/s11604-019-00862-y |
| Popis: | To investigate whether whole-tumor histogram analyses of diffusivity measurements derived from q-space imaging (QSI) improves the differentiation between meningioma and schwannoma. Fifteen extra-axial tumors (11 meningiomas and 4 schwannomas) with MR examinations from April 2011 to May 2013 were included. Three-dimensional regions of interest (ROI) encompassed the whole tumor, including cystic areas. Histogram analyses of mean displacement (MD) derived from QSI and apparent diffusion coefficient (ADC) for the ROI were performed at mean, the five percentiles of MDn and ADCn (n = 5, 25, 50, 75, 95th), kurtosis, and skewness. To determine the diagnostic ability of MDn and ADCn, we also compared the area under the curve (AUC) on receiver operating characteristic (ROC) analysis. Histogram analyses revealed significant differences between meningioma and schwannoma in MD75, ADC25, ADC50, ADC75, and kurtosis of ADC. The ROC analysis of kurtosis of ADC and MD75 resulted in an AUC of 1.0 and 0.96, respectively. There were no significant differences between the AUC of MD75 and that of kurtosis of ADC (p = 0.41). The histogram analyses of MD and ADC derived from QSI were both equally useful in differentiating between intracranial meningioma and schwannoma. |
| Databáze: | OpenAIRE |
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