ω-Ethylenic Allylic Substrates as Alternatives to Cyclic Substrates in Copper- and Iridium-Catalyzed Asymmetric Allylic Alkylation
| Autor: | David Riat, Francesca Giacomina, Alexandre Alexakis |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Allylic rearrangement
Alkylation Molecular Structure Organic Chemistry chemistry.chemical_element Stereoisomerism Ethylenes Iridium Metathesis Biochemistry Copper Combinatorial chemistry Catalysis Allyl Compounds Tsuji–Trost reaction chemistry Cyclization ddc:540 Organometallic Compounds Physical and Theoretical Chemistry |
| Zdroj: | Organic Letters, Vol. 12, No 6 (2010) pp. 1156-1159 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | A new strategy to access highly enantioenriched cyclic compounds (up to 98%) is proposed using omega-ethylenic allylic substrates through a one-pot asymmetric allylic alkylation and ring-closing metathesis. Such starting compounds can be seen as synthetic equivalents of cyclic allylic substrates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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