Early response with clomipramine in obsessive compulsive disorder — A placebo controlled study
| Autor: | D. B. Montgomery, Stuart Montgomery, N.A. Fineberg |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Obsessive-Compulsive Disorder Clomipramine medicine.medical_specialty medicine.drug_class Placebo-controlled study Tricyclic antidepressant Placebo behavioral disciplines and activities Reuptake Placebos Random Allocation Obsessive compulsive Internal medicine mental disorders medicine Humans Psychiatry Biological Psychiatry Depression (differential diagnoses) Psychiatric Status Rating Scales Pharmacology humanities Phobic Disorders Female Serotonin Psychology medicine.drug |
| Zdroj: | Progress in Neuro-Psychopharmacology and Biological Psychiatry. 14:719-727 |
| ISSN: | 0278-5846 |
| DOI: | 10.1016/0278-5846(90)90042-f |
| Popis: | 1. 1. Clomipramine has been found to be effective in the treatment of obsessive compulsive disorder (OCD) in nine placebo controlled studies whereas other conventional antidepressants lacking 5-HT reuptake inhibiting properties do not appear to be effective. 2. 2. The placebo response rate in OCD is very low as is seen in the placebo controlled study of the efficacy of clomipramine 75mg in 14 patients suffering from OCD reported here. 3. 3. Response appears early in treatment when compared with response of depression to antidepressants. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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