Temperature Response in Animals Infected with Bacillus anthracis

Autor:	Ralph E. Lincoln, Albert L. Fernelius, Frederick Klein, Jerry S. Walker
Rok vydání:	1967
Předmět:	Swine Guinea Pigs fungi Temperature Haplorhini Infection and Immunity Biology biology.organism_classification Microbiology Virology Rats Bacillus anthracis Spore Anthrax Pathogenesis Immunity Animals Rabbits Molecular Biology Temperature response
Zdroj:	Journal of Bacteriology. 94:552-556
ISSN:	1098-5530 0021-9193
DOI:	10.1128/jb.94.3.552-556.1967
Popis:	Rats, rabbits, swine, guinea pigs, and monkeys were infected with anthrax spores, and their temperature responses were recorded. These were characteristic for a species and appeared independent of resistance or susceptibility of the species toward establishment of the disease. The rabbit appeared unique in that it not only failed to demonstrate a dose-response relationship over an 8-log dose range, but acted independently producing erratic body temperatures depending on spore dose. This limits the usefulness of the rabbit in studying anthrax pathogenesis, and poses questions regarding published data with the rabbit as the test animal.
Databáze:	OpenAIRE
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