Significant divergences between the temporal structure of the behavior in Wistar and in the spontaneously more anxious DA/Han strain of rats tested in elevated plus maze

Autor: Maurizio Casarrubea, Andrea Santangelo, Vincent Roy, Crescimanno G, Filippina Sorbera, Arnaud Arabo, Magnus S. Magnusson
Přispěvatelé: CASARRUBEA, M, ROY V, SORBERA, F, MAGNUSSON, MS, SANTANGELO, A, ARABO, A, CRESCIMANNO, G., Psychologie et Neurosciences de la Cognition et de l'affectivité (PSY-NCA), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Psychologie et Neurosciences de la Cognition et de l'affectivité ( PSY-NCA ), Université de Rouen Normandie ( UNIROUEN ), Normandie Université ( NU ) -Normandie Université ( NU )
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Male
Elevated plus maze
medicine.medical_specialty
[ SCCO.PSYC ] Cognitive science/Psychology
Anxiety
Settore BIO/09 - Fisiologia
Rats
Mutant Strains
Temporal lobe
Developmental psychology
Rats
Sprague-Dawley
03 medical and health sciences
Behavioral Neuroscience
Basal (phylogenetics)
0302 clinical medicine
Species Specificity
Emotionality
Internal medicine
medicine
Animals
Statistical analysis
Rats
Wistar
Maze Learning
ComputingMilieux_MISCELLANEOUS
Strain (chemistry)
[SCCO.NEUR]Cognitive science/Neuroscience
Anxiety
Elevated plus maze
t-pattern analysis
Multivariate analysis
Wistar
Dark Agouti
Rat
Rats
030227 psychiatry
Endocrinology
[ SCCO.NEUR ] Cognitive science/Neuroscience
Multivariate Analysis
[SCCO.PSYC]Cognitive science/Psychology
Time course
Exploratory Behavior
Temporal organization
Psychology
030217 neurology & neurosurgery
Zdroj: Behavioural Brain Research
Behavioural Brain Research, Elsevier, 2013, 250, pp.166-173. ⟨10.1016/j.bbr.2013.05.016⟩
Behavioural Brain Research, Elsevier, 2013, 250, pp.166-173. 〈10.1016/j.bbr.2013.05.016〉
ISSN: 0166-4328
1872-7549
Popis: The aim of present research is to study the temporal structure of the behavior in two strains of rats with different basal level of emotionality. To this purpose, the temporal profile of the behavior in Wistar rat and in the spontaneously more anxious DA/Han strain was analyzed in the Elevated Plus Maze. Both quantitative and multivariate t-pattern analyses were carried out. In comparison with Wistar, DA/Han subjects showed a significant reduction of the permanence in open arm and a significant increase of the time spent in the central platform of the maze. Mean frequencies of each behavioral element showed significant modifications both in open and in closed arm. Multivariate t-pattern analyses demonstrated a very different temporal profile of behavior in the two strains: Wistar rats presented 197 t-patterns of different composition, whereas DA/Han rats only 26; as to the mean number of t-patterns, Wistar presented a value of 698.90, whereas DA/Han only 92.80. Similar clear-cut differences were detected for the mean number of t-patterns in the two arms and for the time course of such t-patterns. Present study has evidenced that the temporal organization of the bahavior in Elevated Plus Maze is differently structured in two strains of rats with different basal level of emotionality.
Databáze: OpenAIRE
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