Hypersensitivity reactions to modern antiplatelet and anticoagulant drugs
| Autor: | Kathrin Scherer Hofmeier, Andreas J. Bircher |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Allergy
direkt thrombin inhibitors medicine.drug_mechanism_of_action Thienopyridine thienopyridine factor Xa inhibitor business.industry medicine.drug_class Anticoagulant Factor Xa Inhibitor Review Pharmacology medicine.disease Patient management P2Y12 GP IIb/IIIa receptor antagonists Coagulation hyper sensitivity Immunology and Allergy Medicine business Discovery and development of direct thrombin inhibitors |
| Zdroj: | Allergo Journal International |
| ISSN: | 2197-0378 |
| DOI: | 10.1007/s40629-015-0048-2 |
| Popis: | Anticoagulation and antiplatelet drugs are among the most commonly used medical drugs. In addition to the long-established heparins, hirudins, coumarins and antiplatelet drugs such as acetylsalicylic acid, numerous novel and predominantly synthetic pharmacologic agents have come onto the market in recent years. These new agents act at various sites in coagulation and have significantly broadened treatment options. Whilst immunological hypersensitivity reactions are on the whole rare, they have a considerable impact on patient management when they do occur. The present overview discusses the currently known hypersensitivity reactions to anticoagulant and antiplatelet agents, with particular attention to the newer substance classes including P2Y12 inhibitors, glycoprotein IIb/IIIb receptor antagonists, direct factor Xa inhibitors and direct thrombin inhibitors. |
| Databáze: | OpenAIRE |
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