Refractory Acute Interstitial Nephritis in the Setting of Nivolumab Therapy
| Autor: | Tavis Dancik, Antonio Faieta |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
Acute interstitial nephritis medicine.medical_specialty business.industry Urology food and beverages Case Report Disease Diseases of the genitourinary system. Urology 03 medical and health sciences 0302 clinical medicine Refractory Nephrology Male patient 030220 oncology & carcinogenesis Mofetil mycophenolate Medicine RC870-923 Nivolumab business 030304 developmental biology |
| Zdroj: | Case Reports in Nephrology, Vol 2021 (2021) Case Reports in Nephrology |
| ISSN: | 2090-665X 2090-6641 |
| Popis: | A 65-year-old male patient with metastatic CCRCC developed steroid-dependent, grade 3 AIN secondary to nivolumab weeks after its initiation that resulted in 3 hospitalizations with acute renal failure. The patient was started on MM and his AIN was successfully controlled after a 2-year period of follow-up. Refractory renal AIN resulting from PD-1 inhibitor use is rare, and its successful treatment with mofetil mycophenolate with a 2-year follow-up in a patient with metastatic CCRCC has not been reported. This case is important because not only was his renal irAEs controlled but also long-term treatment with MM did not result in progression of metastatic disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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