Calorigenic effect of insulin in hypothermic dogs

Autor: A. Lucas, Tanche M, Therminarias A, Chirpaz Mf
Rok vydání: 1979
Předmět:
Zdroj: Journal of applied physiology: respiratory, environmental and exercise physiology. 47(2)
ISSN: 0161-7567
Popis: In dogs acutely immersed in cold water (8--13 degrees C), oxygen uptake increased approximately sevenfold and colonic temperature rapidly began to decrease. Fifteen minutes after the start of immersion a high level of hyperglycemia was found but no increase in immunoreactive plasma insulin level was observed. Under these conditions exogenous insulin (0.3 U.kg-1) induced a further increase in oxygen uptake and in shivering intensity whereas a decrease in the fall of colonic temperature was observed. It can be concluded that insulin may have a calorigenic effect and improve the resistance to cold of dogs exposed to an acute cold stress.
Databáze: OpenAIRE