Calorigenic effect of insulin in hypothermic dogs
Autor: | A. Lucas, Tanche M, Therminarias A, Chirpaz Mf |
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Rok vydání: | 1979 |
Předmět: |
medicine.medical_specialty
Physiology business.industry Insulin medicine.medical_treatment Hypothermia Oxygen uptake Cold Temperature Exogenous insulin Endocrinology Plasma insulin level Dogs Physiology (medical) Anesthesia Internal medicine Immersion medicine Shivering Animals medicine.symptom business Cold stress Body Temperature Regulation |
Zdroj: | Journal of applied physiology: respiratory, environmental and exercise physiology. 47(2) |
ISSN: | 0161-7567 |
Popis: | In dogs acutely immersed in cold water (8--13 degrees C), oxygen uptake increased approximately sevenfold and colonic temperature rapidly began to decrease. Fifteen minutes after the start of immersion a high level of hyperglycemia was found but no increase in immunoreactive plasma insulin level was observed. Under these conditions exogenous insulin (0.3 U.kg-1) induced a further increase in oxygen uptake and in shivering intensity whereas a decrease in the fall of colonic temperature was observed. It can be concluded that insulin may have a calorigenic effect and improve the resistance to cold of dogs exposed to an acute cold stress. |
Databáze: | OpenAIRE |
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